myTV - Hands down the best Vista application for managing all those archived TV series. It auto downloads banners, series covers, episode synopsis from thetvdb.com.
Will sone be able to be run as a server/client so one database/server can serve multiple machines.
Unfortunately at the moment there is only the commercial build available ($10US) but in the next day or so there will be a trial version. There's been some pretty heavy duty beta testing going on and it's very close.
MCOrganizer - The prettiest movie application out there. Still only early days in development, and uses a paid application called Movie Collector to manage the movies, put it is very nice. If development continues at the pace it has it will be even better.
others I use that have already been mentioned are
BigScreen Weather & BigScreen Photo's.